These patches are more commonly found on sun-exposed areas of the body, including the hands, feet, arms, face, and lips. Other common areas for white patches to appear are the armpits and groin, and around the mouth, eyes, nostrils, navel, genitals, and rectal areas. Vitiligo generally appears in one of three patterns - focal pattern = the depigmentation is limited to one or only a few areas; segmental pattern = depigmented patches develop on only one side of the body; generalized pattern = this is the most common pattern, where depigmentation occurs symmetrically on both sides of the body. In addition to white patches on the skin, people with vitiligo may have premature graying of the scalp hair, eyelashes, eyebrows, and beard. People with dark skin may notice a loss of color inside their mouths. There are many different treatments for vitiligo. One of these include Tacalcitol which is a synthetic vitamin D3 analogue. It is marketed under several names, including Curatoderm and Bonalfa. It exerts its biological activity by preventing the proliferation of keratinocytes.
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